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E-Patient Counseling Trial (E-PACO): Computer Based Education versus Nurse Counseling for Patients to Prepare for Colonoscopy

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Optimal preparation for video capsule endoscopy: a prospective, randomized, single-blind study.

S A C van Tuyl¹, H den Ouden, M F J Stolk

¹Department of Gastroenterology, St. Antonius Hospital Nieuwegein, Nieuwegein, The Netherlands.

|December 12, 2007

Summary

One liter of polyethylene glycol (PEG) solution is an effective and tolerable bowel preparation for video capsule endoscopy (VCE). This method significantly improves small bowel visualization without patient discomfort, enhancing diagnostic potential.

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Area of Science:

Gastroenterology
Medical Imaging
Endoscopy

Background:

Small bowel visualization via video capsule endoscopy (VCE) is often hindered by intestinal contents.
Previous studies on bowel preparation for VCE have yielded inconsistent results.

Purpose of the Study:

To identify an optimal and well-tolerated bowel preparation regimen for VCE.

Main Methods:

A randomized trial involving 90 patients compared three VCE preparation groups: clear liquid diet only, 1 L polyethylene glycol (PEG), and 2 L PEG.
Mucosal visibility was assessed, with good visualization defined as >75% evaluable mucosa.
Patient tolerability was evaluated via questionnaire.

Main Results:

Polyethylene glycol (PEG) significantly enhanced mucosal visualization, particularly in the terminal ileum.
Good visualization rates were 25% (no PEG), 52% (1 L PEG), and 72% (2 L PEG).
Diagnostic yield remained consistent across groups, but 2 L PEG was less comfortable.

Conclusions:

One liter of PEG solution offers a balance of improved mucosal visualization and patient comfort for VCE.
This regimen represents a satisfactory bowel preparation for VCE procedures.