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Updated: Jul 9, 2026

Isolation of Primary Human Decidual Cells from the Fetal Membranes of Term Placentae
Published on: April 30, 2018
[Endometrial decidualization as a factor that regulates cytothrophoblastic invasion during the first trimester of
Abstract:
Endometrial stromal cell decidualization is a multistage process that starts with the late secretory phase of a menstrual cycle and then continues in the first months of pregnancy. Under the influence of the hormone progesterone, precursor cells undergo a unique structural and functional transformation from the adventitional cells of spiral arteries containing a marker of smooth muscles (desmin) through pre-decidual cells to the decidual intermediate cells expressing a marker of the extraembryonic mesoderm (vimentin), and IGFBR-1 and then to the typical epithelioid decidual cells.
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