Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Venous Thrombosis III: Interprofessional Care

Venous Thrombosis III: Interprofessional Care

Venous thrombosis requires effective prevention and treatment strategies to improve patient outcomes and reduce potential complications.Prevention StrategiesHealthcare providers must prioritize preventing venous thromboembolism (VTE) for all adult patients upon admission. Interventions depend on bleeding and thrombosis risk, medical history, current medications, diagnoses, planned procedures, and patient preferences. Patients on bed rest should change positions every two hours and, if not...

Peripheral Artery Disease V: Postoperative Nursing Management

Peripheral Artery Disease V: Postoperative Nursing Management

During the postoperative period, it is crucial to focus on maintaining circulation, identifying and managing potential complications, and planning for discharge.Nursing AssessmentVital signs monitoring: Regularly monitor vital signs, including blood pressure, heart rate, respiratory rate, and temperature, to detect early signs of complications such as bleeding and infection.Circulation assessment: Monitor pulses, perform Doppler assessments, and check capillary refill, color, temperature, and...

Venous Thrombosis I: Introduction

Venous Thrombosis I: Introduction

Venous thrombosis, the most common disorder of the veins, involves the formation of a thrombus or blood clot associated with vein inflammation. It can be classified as either superficial vein thrombosis or deep vein thrombosis.Superficial Vein Thrombosis: This involves the formation of a thrombus in a superficial vein, usually the greater or lesser saphenous vein. Though less severe than deep vein thrombosis (DVT), SVT can lead to complications if untreated.Deep Vein Thrombosis (DVT): This...

Pulmonary Embolism II: Diagnostic Studies and Interprofessional Care

Pulmonary Embolism II: Diagnostic Studies and Interprofessional Care

Diagnosing Pulmonary EmbolismDiagnosing pulmonary embolism (PE) involves clinical assessment and advanced imaging tests. The preferred diagnostic tool is the spiral (helical) CT scan or CT angiography (CTA), which uses intravenous contrast media to visualize the pulmonary vasculature and identify emboli.A ventilation-perfusion (V/Q) scan is an alternative for patients unable to receive contrast media. This scan includes both perfusion and ventilation scanning. Perfusion scanning involves...

Venous Thrombosis IV: Nursing Management

Venous Thrombosis IV: Nursing Management

Nursing management begins with a thorough assessment of the patient's health history. Key factors include trauma to veins, peripherally inserted central catheters, varicose veins, recent pregnancy or childbirth, surgery, bacteremia, prolonged bed rest, atrial fibrillation, COPD, heart failure, cancer, coagulation disorders, myocardial infarction, spinal cord injury, stroke, prolonged travel, recent bone fractures, and dehydration. Review medication intake, particularly oral contraceptives,...

Pulmonary Embolism III: Nursing Management

Pulmonary Embolism III: Nursing Management

A pulmonary embolism occurs when a thrombus, amniotic fluid, tumor tissue, fat, or air embolus blocks one or more pulmonary arteries. Effective nursing management and patient education are crucial for improving outcomes and preventing recurrence.Nursing management starts with obtaining a comprehensive patient history, particularly noting any history of deep vein thrombosis (DVT). Assess for clinical manifestations, including dyspnea, chest pain, crackles, heart murmurs, and signs of right-sided...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

A study survey on molnupiravir treatment in COVID-19 patients at home in Ninh Thuan province, Vietnam.

European review for medical and pharmacological sciences·2024

Same author

The human microbiota key role in the bone metabolism activity.

European review for medical and pharmacological sciences·2023

Same author

The effectiveness of autologous demineralized tooth graft for the bone ridge preservation: a systematic review of the literature.

Journal of biological regulators and homeostatic agents·2021

Same author

The integumentary system and its microbiota between health and disease.

Journal of biological regulators and homeostatic agents·2021

Same author

Gender medicine: the impact of probiotics on male patients.

La Clinica terapeutica·2020

Same author

The role of PIAS3, p-STAT3 and ALR in colorectal cancer: new translational molecular features for an old disease.

European review for medical and pharmacological sciences·2020

Search research articles

Related Experiment Videos

Thromboembolic risk after knee endoprosthesis.

R Prejbeanu¹, H Vermesan, S I Dragulescu

¹University of Medicine and Pharmacy Victor Babes, Timisoara, Romania.

European Review for Medical and Pharmacological Sciences

|December 14, 2007

Summary

Low molecular weight heparin effectively prevents deep vein thrombosis after knee replacement surgery. This anticoagulant therapy significantly reduces thromboembolic risks without a statistically significant increase in bleeding complications.

Related Experiment Videos

Area of Science:

Orthopedic Surgery
Vascular Medicine
Pharmacology

Background:

Thromboembolic complications, particularly deep vein thrombosis (DVT), are common after knee replacement.
Untreated DVT can lead to pulmonary embolism, a potentially fatal outcome.
Antithrombotic prophylaxis is crucial for managing post-knee arthroplasty risks.

Purpose of the Study:

To evaluate the efficacy of low molecular weight heparin in preventing thromboembolic events post-knee arthroplasty.
To assess the incidence of deep vein thrombosis and pulmonary embolism in patients receiving low molecular weight heparin.
To determine the rate of hemorrhagic complications associated with this anticoagulant therapy.

Main Methods:

A cohort of 214 patients undergoing knee arthroplasty were administered low molecular weight heparin.
Patients were monitored for thromboembolic and hemorrhagic complications using clinical evaluation and imaging (ultrasonography, phlebography) at specific intervals (2nd, 7th, 14th, and 45th day post-surgery).

Main Results:

Deep vein thrombosis (DVT) was detected in 45% of patients, with 17% confirmed by imaging.
One case of fatal massive pulmonary embolism was recorded.
No major bleeding events occurred; four cases of local hematomas were observed, possibly linked to anticoagulation.

Conclusions:

Low molecular weight heparin significantly reduces the risk of thromboembolism following knee arthroplasty.
The observed increase in hemorrhagic complications was not statistically significant, indicating a favorable safety profile.
Anticoagulant prophylaxis with low molecular weight heparin is recommended for patients undergoing knee replacement surgery.