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Updated: Jul 9, 2026
PET and MRI Guided Irradiation of a Glioblastoma Rat Model Using a Micro-irradiator
Published on: December 28, 2017
Photon radiotherapy for the treatment of high-grade gliomas
Catherine S Hwang1, Maryann H Marymont, Kenji Muro
1Northwestern University, Department of Radiation Oncology, Feinberg School of Medicine, 251 East Huron Avenue, Galter Pavilion LC-178, Chicago, IL 60611, USA. chwang003@md.northwestern.edu
Abstract:
High-grade gliomas are diseases characterized by poor overall survival despite aggressive multimodality therapy. Radiation therapy has been unequivocally established as the mainstay of therapy after surgical intervention, regardless of the extent of surgical resection. Despite theoretical and technological advances in the planning and delivery of radiation therapy, overall survival remains grim. In this review, we outline the evolution of radiation therapy, report the pivotal trials that have shaped this therapy and speculate on the future direction of this field.
