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Related Concept Videos

Bone Disorders01:29

Bone Disorders

Aging and its effect on bone remodeling is the most common cause of bone disorders. In young and healthy people, bone deposition and resorption happen at an equal rate to maintain optimal bone health.
Bone deposition is also affected by the levels of sex hormones like estrogen and testosterone that promote osteoblast activity and bone matrix synthesis. When the level of these hormones decreases due to aging, it causes a reduction in bone deposition. As a result, bone resorption by osteoclasts...
Disorders of the Skeletal Muscle01:28

Disorders of the Skeletal Muscle

The clinical conditions affecting the skeletal muscle tissue are broadly categorized as musculoskeletal and neuromuscular disorders.
Musculoskeletal disorders
Musculoskeletal disorders involve injuries and conditions affecting the skeletal muscles and associated connective tissues. These disorders can arise from acute biomechanical stresses or chronic overuse and can occur across different age groups. Common injuries include sprains, fractures, and muscular strains, often resulting from...
The Functions of the Skeletal System01:22

The Functions of the Skeletal System

The most apparent functions of the skeletal system are support, protection, and movement. However, bone tissue also performs several other critical metabolic functions. For one, the bone matrix acts as a reservoir for a number of minerals important to the functioning of the body, especially calcium and phosphorus. These minerals, present in the bone tissue, can be released back into the bloodstream when required. Calcium ions, for example, are essential for muscle contractions and controlling...
What is the Skeletal System?01:02

What is the Skeletal System?

Overview
Introduction to the Skeletal System01:20

Introduction to the Skeletal System

The skeletal system is the central framework of the body, consisting of different connective tissues: bones, cartilage, tendons, and ligaments.
Components of the Skeletal System
Bone, or osseous tissue, is a hard connective tissue that forms an internal support structure for the human body. Bones shield vulnerable organs and soft tissue from external forces. For example, the vertebral bones protect and support the spinal cord.
Cartilage, a semi-rigid connective tissue found in regions such as...
Vertebral Column: Regions and Curvature01:16

Vertebral Column: Regions and Curvature

The vertebral column or spine is a flexible column that supports the head, neck, and body and  allows for their movements. It also protects the spinal cord.
Regions of the Vertebral Column
In an adult, the spine is subdivided into five regions: the cervical, the thoracic, the lumbar, the sacral, and the coccygeal region. The spine initially develops as a series of 33 vertebrae; after 20 years of age, the nine bones in the sacral region, five sacral, and four coccygeal bones fuse to form the...

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Temporary screw epiphyseodesis of the first metatarsal for correction of juvenile hallux valgus.

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Outcome After Combined Pelvic and Femoral Osteotomies in Patients with Legg-Calvé-Perthes Disease.

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Related Experiment Video

Updated: Jul 9, 2026

Minimally Invasive Treatment for Thoracolumbar Burst Fracture Using Sagittal Alignment Screws and A Trauma Reduction Device
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[Spinal problems in persons with skeletal dysplasias].

R Stücker1

  • 1Altonaer Kinderkrankenhaus, Bleickenallee 38, 22763 Hamburg, Deutschland. stuecker@akkev.net

Der Orthopade
|December 15, 2007
PubMed
Summary

Most skeletal dysplasias cause short stature and spinal issues. This review covers spinal problems, diagnosis, and treatments for skeletal dysplasia patients.

Area of Science:

  • Orthopedics
  • Genetics
  • Pediatrics

Background:

  • Skeletal dysplasias are a group of genetic disorders affecting bone and cartilage development.
  • While short stature is a common feature, spinal deformities are also prevalent but less recognized.
  • These spinal complications can significantly impact patient health and quality of life.

Purpose of the Study:

  • To provide a comprehensive overview of spinal problems associated with skeletal dysplasias.
  • To discuss diagnostic approaches for identifying spinal abnormalities in affected individuals.
  • To review current and emerging treatment strategies for managing these spinal conditions.

Main Methods:

  • Literature review of studies on skeletal dysplasias and spinal complications.

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Minimally Invasive Treatment for Thoracolumbar Burst Fracture Using Sagittal Alignment Screws and A Trauma Reduction Device
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Training Persons with Spinal Cord Injury to Ambulate Using a Powered Exoskeleton

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  • Analysis of diagnostic imaging techniques and genetic testing relevant to spinal assessment.
  • Synthesis of information on surgical and non-surgical treatment modalities.

    • Main Results:

    • Skeletal dysplasias frequently present with diverse spinal pathologies, including scoliosis, kyphosis, and vertebral anomalies.
    • Early and accurate diagnosis relies on a combination of clinical evaluation, advanced imaging (MRI, CT), and genetic analysis.
    • Treatment is individualized, ranging from conservative management to complex surgical interventions aimed at correcting deformities and preventing neurological compromise.

    Conclusions:

    • Spinal problems are a critical, often underestimated, aspect of skeletal dysplasias.
    • Multidisciplinary management involving orthopedic surgeons, geneticists, and rehabilitation specialists is essential.
    • Ongoing research into novel therapeutic approaches promises improved outcomes for patients with skeletal dysplasia-related spinal conditions.