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Updated: Jan 20, 2026
Palladium-Catalyzed Cross Coupling; Heck Coupling Reaction
Published on: April 29, 2023
A facile synthesis of 2-methylquinolines via Pd-catalyzed aza-wacker oxidative cyclization
Zuhui Zhang1, Jiajing Tan, Zhiyong Wang
1Hefei National Laboratory for Physical Science at Microscale, Joint Laboratory of Green Synthetic Chemistry and Department of Chemistry, University of Science and Technology of China, Hefei, Anhui, 230026, People's Republic of China.
Abstract:
A novel Pd-catalyzed Wacker-type oxidative cyclization under air is described. By using this cyclization, a series of 2-methylquinolines are readily prepared with good yields under mild conditions.
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