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[Blood pressure control in hypertensive patients with left ventricular hypertrophy. The VIIDA Study]
Vicente Bertomeu1, Lorenzo Fácila, José R González-Juanatey
1Servicio de Cardiología, Hospital San Juan de Alicante, Alicante, España.
Insights
Blood pressure control is poor in hypertensive patients with left ventricular hypertrophy (LVH), especially those with diabetes. Factors like female sex and higher BMI predict poor control, while cardiovascular disease history is linked to better control.
Area of Science:
- Cardiology
- Hypertension Research
- Electrocardiography
Context:
- Left ventricular hypertrophy (LVH) is common in hypertensive patients attending cardiology clinics.
- Comorbid conditions, particularly diabetes, are prevalent in this population.
- Electrocardiogram (ECG) is used for LVH detection.
Purpose:
- To assess blood pressure (BP) control effectiveness in hypertensive patients with ECG-detected LVH.
- To identify variables associated with poor BP control, with a focus on diabetic patients.
Summary:
- A high prevalence of LVH was observed in 16,123 hypertensive patients (25.04%).
- BP control was suboptimal, with only 8.1% of diabetic patients achieving target BP (<130/80 mmHg) compared to 22.4% of non-diabetics.
- Independent predictors of poor BP control included diabetes, female sex, increased V5 voltage, and higher BMI. Cardiovascular disease history was associated with better control.
Impact:
- Highlights the significant challenge of BP management in hypertensive patients with LVH, particularly those with diabetes.
- Identifies key demographic and clinical factors influencing BP control, aiding targeted interventions.
- Underscores the need for improved hypertension management strategies in this high-risk patient group.
Introduction And Objectives:
The aims were to determine the effectiveness of blood pressure (BP) control in hypertensive patients with left ventricular hypertrophy (LVH), as detected by ECG, and to identify the variables associated with poor control, particularly in diabetics.
Methods:
The study included hypertensive patients with ECG evidence of LVH who attended cardiology outpatient clinics between April 2003 and November 2004. Patient characteristics and clinical variables were recorded on admission to the study.
Results:
Of the 16,123 patients included, 4037 (25.04%) had LVH at presentation. Some 58.1% of these latter patients had a history of cardiovascular disease. Only 8.1% of diabetic patients had BP values below 130/80 mmHg, whereas 22.4% of nondiabetic patients were well-controlled. Multivariate analysis showed that the only independent predictors of poor BP control were diabetes (odds ratio [OR] 3.62, 95% confidence interval [CI] 2.7-4.7), female sex (OR 1.18, 95% CI 1.02-1.33), increased voltage recording in lead V5 (OR 1.027 per mm, 95% CI 1.01-1.03), and body mass index (OR 1.03, 95% CI 1.00-1.05), whereas a history of cardiovascular disease was associated with good BP control (OR 0.57, 95% CI 0.48-0.70).
Conclusions:
The prevalence of LVH, as identified by ECG, was high in hypertensive patients attending cardiology outpatient clinics, and comorbid conditions were common. Control of BP was suboptimal, particularly in diabetic patients, fewer than 10% of whom were well-controlled. Finally, BP control in patients with LVH was influenced by sex, body mass index, and a history of cardiovascular disease.
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