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Using Fluorescent Proteins to Monitor Glycosome Dynamics in the African Trypanosome
Published on: August 19, 2014
Effect of hydroxyurea on procyclic Trypanosoma brucei: an unconventional mechanism for achieving synchronous growth
Arnab Roy Chowdhury1, Zhixing Zhao, Paul T Englund
1Department of Biological Chemistry, Johns Hopkins School of Medicine, Baltimore, MD 21205, USA.
Eukaryotic Cell
|December 18, 2007
Abstract:
Procyclic Trypanosoma brucei cells were synchronized with 0.2 mM hydroxyurea. The cells did not arrest at the G(1)/S boundary but proceeded through one round of replication and arrested near the end of S phase. The mitochondrial genome (kinetoplast DNA network) replicated, forming two progeny networks, but the repair of minicircle gaps was inhibited.

