Human articular chondrocytes culture

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A 3D System for Culturing Human Articular Chondrocytes in Synovial Fluid
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A 3D System for Culturing Human Articular Chondrocytes in Synovial Fluid

Published on: January 31, 2012

Andrea Barbero1, Ivan Martin

  • 1Institute for Surgical Research and Hospital Management, University Hospital Basel, Switzerland.

Methods in Molecular Medicine
|December 19, 2007
PubMed

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Chondrocytes form a temporary cartilaginous model by dividing and secreting a thick gel-like extracellular matrix. Once the chondrocytes undergo programmed cell death, osteoblasts enter the site of the cartilaginous model. The process of replacing the temporary cartilaginous model with bone in an ordered manner is called endochondral ossification. In endochondral ossification, not all of the cartilage is replaced by bone tissue. Some cartilage that performs a protective and supportive function...