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Updated: Jul 9, 2026

MicroRNA-based Regulation of Picornavirus Tropism
Published on: February 6, 2017
The functions of herpesvirus-encoded microRNAs
Finn Grey1, Lauren Hook, Jay Nelson
1Vaccine and Gene Therapy Institute, Oregon Health Sciences University, 505 NW 185th Ave, Portland, OR 97006, USA. greyf@ohsu.edu
Abstract:
Bioinformatic and direct cloning approaches have led to the identification of over 100 novel miRNAs expressed in DNA viruses, although the function of the majority of these small regulatory RNA molecules is unclear. Recently, a number of reports have now identified potential targets of viral miRNAs, including cellular and viral genes as well as an ortholog of an important immuno-regulatory cellular miRNA. In this review, we will cover the identification and characterization of miRNAs expressed in the herpesvirus family and discuss the potential significance of their role in viral infection.
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