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Updated: Jul 9, 2026
A Mouse Distraction Osteogenesis Model
Published on: November 14, 2018
Distraction osteogenesis of the midface.
George K B Sándor1, Leena P Ylikontiola, Willy Serlo
1University of Toronto, Toronto, Ontario, Canada; The Hospital for Sick Children S-525, 555 University Avenue, Toronto, Ontario, Canada M5G 1X8; Bloorview MacMillan Children's Centre, 170 Kilgour Road, Toronto, Ontario, Canada M4G 1R8; Department of Oral and Maxillofacial Surgery, Mount Sinai Hospital, Toronto, Ontario, Canada; Department of Oral and Maxillofacial Surgery, University of Oulu, Oulu, Finland; Institute of Dentistry, University of Oulu, Box 5281 FIN-90014, Finland.
Distraction osteogenesis is key in pediatric oral surgery, particularly for midface reconstruction. This technique addresses growth issues from congenital conditions, tumors, and trauma across various facial sites.
Area of Science:
- Pediatric Oral and Maxillofacial Surgery
- Craniofacial Reconstruction
Background:
- Distraction osteogenesis is a vital surgical technique.
- It is particularly effective for midface reconstruction in pediatric patients.
- Congenital malformations, tumors, and trauma often necessitate midfacial interventions.
Purpose of the Study:
- To review the application of distraction osteogenesis in the pediatric midface.
- To highlight anatomical site variations for midfacial distraction techniques.
- To discuss the differences in applying distraction osteogenesis at various midfacial locations.
Main Methods:
- Review of current literature on midfacial distraction osteogenesis.
- Analysis of anatomical considerations for distraction techniques.
- Comparison of application methods across different midfacial skeletal sites.
Main Results:
- Distraction osteogenesis offers diverse applications within the midfacial skeleton.
- Specific anatomical sites require tailored distraction approaches.
- Technique modifications are crucial for successful outcomes at different locations.
Conclusions:
- Midfacial distraction osteogenesis is a versatile tool in pediatric oral and maxillofacial surgery.
- Understanding anatomical variations is essential for optimal treatment planning.
- Tailored application of distraction techniques ensures effective correction of midfacial deformities.
