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Published on: November 9, 2017
HIV infection presenting with motor axonal variant of Guillain-Barré Syndrome
Jeffrey C Wagner1, Mark B Bromberg
1Department of Neurology, University of Utah, Salt Lake City, UT, USA. Jeffrey.wagner@hsc.utah.edu
Objectives:
We present a case of acute motor axonal neuropathy in a patient with previously unrecognized human immunodeficiency virus (HIV) infection.
Methods:
A 46-year-old male graduate student from Mali, Africa presented with a 3-week history of progressive weakness that began during a visit home from Utah. The symptoms stabilized by 6 weeks and gradually improved without treatment.
Results:
Electrodiagnostic studies revealed widespread fibrillation potentials and positive sharp waves with normal sensory amplitudes and no demyelinating features. Cerebrospinal fluid pleocytosis and elevated protein prompted a test for HIV infection, which returned positive.
Conclusions:
To our knowledge, this is the first case of acute motor axonal neuropathy in HIV outside of a seroconversion reaction.
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