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Array Tomography Workflow for the Targeted Acquisition of Volume Information using Scanning Electron Microscopy
Published on: July 15, 2021
An overview of fast convergent ordered-subsets reconstruction methods for emission tomography based on the
Ing-Tsung Hsiao1, Parmeshwar Khurd, Anand Rangarajan
1Dept. of Medical Imaging and Radiological Sciences, Chang Gung University, 333 Tao-yuan, Taiwan.
We introduce Complete-data OSEM (COSEM), a novel statistical reconstruction algorithm for emission computed tomography. COSEM offers fast convergence for both Maximum Likelihood (ML) and Maximum A Posteriori (MAP) solutions without needing a relaxation schedule.
Area of Science:
- Medical Imaging
- Computational Science
- Statistical Modeling
Background:
- Statistical reconstruction is crucial for emission computed tomography (ECT) but often exhibits slow convergence.
- Existing methods like OSEM are fast but non-convergent, while convergent algorithms (RAMLA, BSREM) require user-defined relaxation schedules.
Purpose of the Study:
- To develop a fast and convergent statistical reconstruction algorithm for ECT.
- To address the limitations of existing algorithms by eliminating the need for a relaxation schedule.
Main Methods:
- Proposed Complete-data OSEM (COSEM) algorithms for both ML and MAP cases.
- COSEM is derived as a form of incremental EM algorithm.
- Demonstrated COSEM performance using simulations.
Main Results:
- COSEM achieves fast convergence for both ML and MAP solutions in ECT.
- COSEM avoids the use of a relaxation schedule while maintaining convergence.
- COSEM-ML and COSEM-MAP show competitive performance compared to existing methods, with potential for further optimization.
Conclusions:
- COSEM provides an effective solution for accelerating statistical reconstruction in ECT.
- The algorithm's ability to maintain convergence without a relaxation schedule simplifies its application.
- Further modifications to COSEM can potentially overcome early-iteration speed limitations.
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