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Updated: Jul 9, 2026

Characterizing the Relationship Between Eye Movement Parameters and Cognitive Functions in Non-demented Parkinson's Disease Patients with Eye Tracking

Characterizing the Relationship Between Eye Movement Parameters and Cognitive Functions in Non-demented Parkinson's Disease Patients with Eye Tracking

Published on: September 26, 2019

Cognitive function assessment in idiopathic Parkinson's disease.

Mauro R Piovezan¹, Helio A G Teive, Elcio J Piovesan

¹Neurology Division, Internal Medicine Department, Hospital de Clinicas, Universidade Federal do Paraná, Rua General Carneiro 181, Curitiba, PR, Brazil.

Arquivos De Neuro-Psiquiatria

|December 21, 2007

Summary

This study investigated cognitive impairment in Parkinson's disease (PD). Results show significant differences in cognitive, verbal, and executive functions between PD patients and controls, highlighting the impact of PD on brain function.

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Dynamic Digital Biomarkers of Motor and Cognitive Function in Parkinson's Disease

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Dynamic Digital Biomarkers of Motor and Cognitive Function in Parkinson's Disease

Dynamic Digital Biomarkers of Motor and Cognitive Function in Parkinson's Disease

Published on: July 24, 2019

Area of Science:

Neuroscience
Neurology
Cognitive Science

Background:

Idiopathic Parkinson's disease (PD) involves reduced dopaminergic influence, leading to motor, behavioral, and cognitive issues.
Cognitive impairment is a significant, often under-recognized, aspect of Parkinson's disease progression.

Purpose of the Study:

To assess and compare cognitive functions in patients with idiopathic Parkinson's disease versus a healthy control group.
To identify specific domains of cognitive impairment in Parkinson's disease patients.

Main Methods:

A cohort of 30 idiopathic Parkinson's disease (PD) patients and 30 controls were evaluated.
Assessments included motor function (UPDRS), depression (Montgomery-Asberg), and various cognitive tests (MMSE, verbal fluency, visuospatial, executive functions, clock drawing).

Main Results:

Parkinson's disease patients exhibited statistically significant deficits in cognitive, verbal, executive, and visuospatial functions compared to controls.
Attention deficits were also significantly more prevalent in the PD group.
Depression was found to be more common in the Parkinson's disease patient group.

Conclusions:

Idiopathic Parkinson's disease is associated with widespread cognitive impairments beyond motor symptoms.
Cognitive, verbal, executive, and visuospatial deficits, along with attention impairments, are key features of PD.
The study underscores the need for comprehensive cognitive assessment in Parkinson's disease management.