Related Experiment Video
Updated: Jan 28, 2026
Induction of Paralysis and Visual System Injury in Mice by T Cells Specific for Neuromyelitis Optica Autoantigen Aquaporin-4
Published on: August 21, 2017
Somatosensory evoked potentials in neuromyelitis optica spectrum disorders
Otto Jesus Hernandez Fustes1, Cláudia Suemi Kamoi Kay1, Paulo José Lorenzoni1
1Departamento de Clínica Médica, Hospital de Clínicas, Serviço de Neurologia, Serviço de Doenças Neuromusculares, Universidade Federal do Paraná, Curitiba, Brasil.
Introduction:
Neuromyelitis optica spectrum disorders (NMOSD) are rare antibody-mediated disorders of the central nervous system with a predilection for the spinal cord and optic nerves.
Objective:
Our objective is to evaluate the dorsolemniscal system using the somatosensory evoked potential, specifically the registration of the N20 and P40 waves.
Methods:
The Somatosensory evoked potentials (SSEP) were prospectively performed in 13 patients with NMOSD. All the patients were recruited from the outpatient clinic of a demyelinating diseases center from Southern Brazil.
Results:
We evaluated 12 female with mean age of 42 years-old and one man of 25 years-old. When categorized in relation to the variable SSEP (Normal vs. Abnormal), there was a statistical difference in relation to N20, N21 and P40 latencies.
Conclusion:
SSEP showed a significant increase in N20 and P40 latencies. SSEP is a non-invasive, painless, fast and low-cost exam which provides neurophysiological data for diagnosis of NMOSD.
More Related Videos
Related Concept Videos
01:19Autism Spectrum Disorder
These core symptoms manifest differently among individuals, ranging from mild to severe. The disorder's complexity extends beyond its clinical presentation, encompassing a diverse range of biological, cognitive, and sociocultural influences.
02:37The Electromagnetic Spectrum
01:24The Electromagnetic Spectrum
01:19IR Spectrum
Transmittance is defined as the ratio of the radiant power passing through a sample to that from the radiation's source. Multiplying the transmittance by 100 gives the percent transmittance (%T), which varies between 100% (no absorption) and 0%...
01:23Mass Spectrum
01:11Sensory Perception: Organization of the Somatosensory System
The receptor level:
The receptor level is the first stage of sensation. It involves the detection of a stimulus by specialized sensory receptors. The stimulus must arrive within the receptor's receptive field. Next, the receptor converts the energy of the...