[Celiac disease associated with Budd-Chiari syndrome]

Area of Science:

• Hepatology
• Gastroenterology
• Immunology

Background:

• Budd-Chiari syndrome involves hepatic portal vein obstruction.
• Celiac disease is an autoimmune disorder triggered by gluten.
• The co-occurrence of these conditions is exceptionally rare.

Observation:

• A 28-year-old woman presented with coexisting celiac disease and Budd-Chiari syndrome.
• No identifiable cause was found for the Budd-Chiari syndrome in this patient.

Findings:

• Treatment with a gluten-free diet and antivitamin K therapy resulted in a favorable clinical outcome.
• This case, alongside literature review, indicates a potential shared pathogenesis between the two disorders.

Implications:

• The findings suggest a possible link between the autoimmune processes in celiac disease and the vascular complications seen in Budd-Chiari syndrome.
• Further research into this association may reveal novel diagnostic or therapeutic strategies for both conditions.