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Monitoring Protein-RNA Interaction Dynamics In Vivo at High Temporal Resolution Using χCRAC
09:15

Monitoring Protein-RNA Interaction Dynamics In Vivo at High Temporal Resolution Using χCRAC

Published on: May 9, 2020

Visualizing spatially correlated dynamics that directs RNA conformational transitions.

Qi Zhang1, Andrew C Stelzer, Charles K Fisher

  • 1Department of Chemistry and Biophysics, University of Michigan, 930 North University Avenue, Ann Arbor, Michigan 48109-1055, USA.

Nature
|December 22, 2007
PubMed
Summary

Researchers visualized RNA dynamics using NMR, revealing structured movements that guide ligand-induced conformational changes. This study uncovers how RNA flexibility directs transitions along specific pathways.

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