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[Midline malignant reticulosis: a histopathological, ultrastructural and immunohistochemical study of 11 cases]
1Department of Pathology, Chongqing University of Medical Sciences.
Eleven cases of midline malignant reticulosis were studied morphologically, and the monoclonal antibodies used were capable of phenotyping malignant lymphomas in routinely fixed and processed tissue, such as the leukocyte common antigen (LCA), pan-T cell marker UCHL-1 and pan-B cell marker Ki-B3 etc. The results indicated that the 11 cases of midline malignant reticulosis were peripheral T cell lymphomas. According to the updated Kiel's classification, 7 cases were low grade pleomorphic small cell type; the other 4 cases were high grade pleomorphic medium and large cell type of peripheral T cell lymphoma. The diagnosis, differential diagnosis, cell origin and gradation of midline malignant reticulosis are discussed.
Eleven cases of midline malignant reticulosis were studied morphologically, and the monoclonal antibodies used were capable of phenotyping malignant lymphomas in routinely fixed and processed tissue, such as the leukocyte common antigen (LCA), pan-T cell marker UCHL-1 and pan-B cell marker Ki-B3 etc. The results indicated that the 11 cases of midline malignant reticulosis were peripheral T cell lymphomas. According to the updated Kiel's classification, 7 cases were low grade pleomorphic small cell type; the other 4 cases were high grade pleomorphic medium and large cell type of peripheral T cell lymphoma. The diagnosis, differential diagnosis, cell origin and gradation of midline malignant reticulosis are discussed.