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[The diagnostic value of version 2.1 prostate imaging reporting and data system for prostate transitional zone
S Yang1, C Y Zhang1, Y Y Zhang1
1Department of Imaging, Second Affiliated Hospital of Soochow University, Suzhou 215004, China.
Zhonghua Yi Xue Za Zhi
|December 17, 2020
Summary
The Prostate Imaging Reporting and Data System (PI-RADS) version 2.1 shows improved consistency for scoring prostate transitional zone lesions compared to version 2. While diagnostic efficiency is similar, PI-RADS 2.1 offers slightly higher sensitivity and AUC values for detecting prostate cancer.
Area of Science:
- Radiology
- Urology
- Oncology
Background:
- The Prostate Imaging Reporting and Data System (PI-RADS) is crucial for standardizing prostate MRI interpretation.
- Version 2.1 of PI-RADS was developed to refine diagnostic criteria.
- Evaluating PI-RADS 2.1's performance in transitional zone lesions is important for clinical application.
Purpose of the Study:
- To compare the diagnostic value of PI-RADS version 2.1 and version 2 for prostate transitional zone lesions.
- To assess the inter-observer consistency and diagnostic efficiency of both PI-RADS versions.
Main Methods:
- Retrospective analysis of 159 patients with prostate transitional zone lesions.
- Two radiologists independently scored lesions using PI-RADS V2.1 and V2.
- Weighted Kappa test for inter-observer consistency.
- ROC curve analysis for diagnostic efficiency in detecting prostate cancer (PCa) and clinically significant PCa (csPCa).
Main Results:
- PI-RADS V2.1 demonstrated better inter-observer consistency (Kappa values: 0.754-0.782) compared to PI-RADS V2 (Kappa values: 0.643-0.738).
- No statistically significant differences in sensitivity, specificity, or AUC were found between the two versions (P>0.05).
- PI-RADS V2.1 showed numerically higher sensitivity and AUC for PCa and csPCa detection.
Conclusions:
- PI-RADS version 2.1 offers improved consistency for scoring prostate transitional zone lesions over PI-RADS V2.
- The diagnostic efficiency of PI-RADS 2.1 is comparable to, and potentially slightly better than, PI-RADS V2 for transitional zone prostate cancer.
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