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Serum soluble interleukin-2 receptor levels of normal blood donors
D J Giannitsis1, B Müller-Hof, B Häcker-Shahin
1Klinikum Karlsruhe, Akademisches Lehrkrankenhaus, Universität Freiburg, Germany.
Following T cell activation a part of the IL-2-receptor (sIL-2-R) was released from the T cell membrane. Elevated serum levels of sIL-2-R were observed in some pathological conditions. The serum of healthy blood donors (n = 228) was investigated by ELISA to see whether a correlation existed in normal donors between the age or the sex of the donor and the sIL-2-R. The serum levels found were in the range between 5 and 398 pM. No correlation was found between the different ages or the sex of the donors.
Following T cell activation a part of the IL-2-receptor (sIL-2-R) was released from the T cell membrane. Elevated serum levels of sIL-2-R were observed in some pathological conditions. The serum of healthy blood donors (n = 228) was investigated by ELISA to see whether a correlation existed in normal donors between the age or the sex of the donor and the sIL-2-R. The serum levels found were in the range between 5 and 398 pM. No correlation was found between the different ages or the sex of the donors.
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