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Related Experiment Videos

Ocular cicatricial pemphigoid.

M R Vandeveer1

  • 1V.A. Medical Center, Battle Creek, MI 49016.

Journal of the American Optometric Association
|March 1, 1991
PubMed
Summary
This summary is machine-generated.

Cicatricial pemphigoid is an autoimmune inflammatory disease affecting the eyes and mouth. Ocular surgery and medications can worsen this condition, requiring systemic treatments.

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Area of Science:

  • Ophthalmology
  • Immunology
  • Dermatology

Background:

  • Cicatricial pemphigoid is an inflammatory condition with an autoimmune cause.
  • It primarily impacts the conjunctiva and oral mucosa, with less frequent skin involvement.

Observation:

  • Ocular manifestations include bilateral conjunctival shrinkage, xerosis, and corneal opacification.
  • The disease progression is unpredictable, marked by remissions and exacerbations.

Findings:

  • Ocular surgery and topical medications can exacerbate cicatricial pemphigoid.
  • Current treatments involve systemic immunosuppressants and corticosteroids.

Implications:

  • Understanding disease triggers is crucial for managing cicatricial pemphigoid.
  • Systemic therapies are the mainstay for controlling this autoimmune condition.