Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Prevention of renal osteodystrophy.

L R Baker1

  • 1St. Bartholomew's Hospital, London, UK.

Mineral and Electrolyte Metabolism
|January 1, 1991
PubMed
Summary

Preventing renal osteodystrophy in kidney disease is crucial. Early interventions like dietary changes and vitamin D analogs may delay bone disease, but long-term benefits require further study.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Isolation and identification of the gibberellins of Cucumis sativus and Cucumis melo.

Planta·2014
Same author

Inspection of surface flaws by comparator microscopy.

Applied optics·2010
Same author

Prevention of contrast nephropathy after cardiac catheterisation.

Heart (British Cardiac Society)·2001
Same author

Reduction of left ventricular mass index with blood pressure reduction in chronic renal failure.

Clinical nephrology·1999
Same author

Preoperative imaging of parathyroid glands.

Lancet (London, England)·1999
Same author

Temporary vascular access for first dialysis is common, undesirable and usually avoidable.

Clinical nephrology·1999

Area of Science:

  • Nephrology
  • Endocrinology
  • Bone Metabolism

Background:

  • Impaired renal function often leads to bone disease (renal osteodystrophy).
  • This condition is associated with hyperparathyroidism and hypercalcemia, necessitating interventions.
  • Extraosseous consequences of hyperparathyroidism also require management.

Purpose of the Study:

  • To review and discuss prevention strategies for renal osteodystrophy.
  • To explore approaches for early, moderate, and end-stage renal failure.
  • To assess the potential benefits and costs of prophylactic measures.

Main Methods:

  • Review of current literature on renal osteodystrophy prevention.
  • Discussion of dietary phosphorus restriction.
  • Evaluation of phosphorus binders, acidosis control, calcium supplementation, and vitamin D analogs (calcitriol, synthetic analogs).

Main Results:

  • Several strategies can delay the onset of severe renal osteodystrophy.
  • The effectiveness of these strategies in reducing parathyroid surgery or improving patient outcomes is not yet established.
  • Financial costs and complication rates of prophylaxis need further definition.

Conclusions:

  • Early prevention of renal osteodystrophy is logical but requires more evidence on long-term benefits.
  • An individualized patient approach is recommended for managing renal impairment and associated bone disease.
  • Further research is needed to define the true cost-effectiveness of preventive strategies.

Related Experiment Videos