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Related Experiment Videos

Airway pressure triggered ventilation for preterm neonates.

A Greenough1, M F Hird, V Chan

  • 1Department of Child Health, King's College Hospital, London, U.K.

Journal of Perinatal Medicine
|January 1, 1991
PubMed
Summary

The SLE 2000 infant ventilator effectively supports preterm newborns using patient-triggered ventilation (PTV), maintaining consistent settings without inadvertent positive end-expiratory pressure (PEEP) even at high rates.

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Area of Science:

  • Neonatal Medicine
  • Respiratory Physiology
  • Medical Device Engineering

Background:

  • Preterm infants often require mechanical ventilation due to respiratory distress syndrome (RDS).
  • Conventional ventilation methods may not always synchronize optimally with infant respiratory efforts.
  • Patient-triggered ventilation (PTV) aims to improve synchrony between the infant and the ventilator.

Purpose of the Study:

  • To assess the efficacy of the SLE 2000 infant ventilator in patient-triggered mode for preterm neonates.
  • To evaluate the performance of the SLE 2000, specifically its triggering capabilities and impact on respiratory parameters.

Main Methods:

  • A prospective study involving 13 preterm infants with RDS.
  • Infants received ventilation for one hour each on a conventional ventilator, the SLE 2000 in conventional mode, and the SLE 2000 in PTV mode.

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  • Arterial blood gases were analyzed hourly. Trigger delay was calculated by measuring the time lag between spontaneous inspiration onset and ventilator breath onset.

    • Main Results:

    • The SLE 2000 demonstrated effective performance at high ventilation rates (up to 150 bpm) without causing inadvertent positive end-expiratory pressure (PEEP).
    • During PTV, peak inspiratory pressure, inspiratory time, and inspired oxygen concentration remained consistent with conventional settings.
    • Trigger delay analysis indicated the time lag between infant effort and ventilator response.

    Conclusions:

    • The SLE 2000 infant ventilator is a capable device for patient-triggered ventilation in preterm neonates.
    • PTV with the SLE 2000 maintains stable respiratory parameters and may offer improved synchrony for infants with RDS.
    • Further research is warranted to fully elucidate the benefits of PTV in this population.