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Prenatal serologic screening in Bahrain.

A A Yousif1, M R Wallace, B H Baig

  • 1Department of Pathology, Salmaniya Medical Centre, Manama, Bahrain.

Scandinavian Journal of Infectious Diseases
|January 1, 1991
PubMed
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Prenatal screening in Bahrain revealed high antibody prevalence for cytomegalovirus (CMV), herpes simplex virus (HSV), and rubella. Routine testing for rubella, syphilis, and hepatitis B is recommended for all pregnant individuals.

Area of Science:

  • Medical Microbiology
  • Infectious Diseases
  • Public Health

Background:

  • Serological surveys are crucial for understanding local disease prevalence.
  • Prenatal screening tests require ongoing assessment for clinical utility.
  • Bahrain's Salmaniya Medical Center conducted disease prevalence studies between 1988-1990.

Purpose of the Study:

  • To determine the prevalence of specific infectious agents in pregnant women in Bahrain.
  • To evaluate the clinical value of various prenatal screening tests.
  • To inform recommendations for routine prenatal screening protocols.

Main Methods:

  • Serological surveys were conducted between 1988 and 1990.
  • Antibody prevalence was assessed for cytomegalovirus (CMV), herpes simplex virus (HSV), rubella, Toxoplasma gondii, hepatitis B surface antigen (HBsAg), and Treponema pallidum.

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  • Data analysis focused on seroprevalence rates.

    • Main Results:

    • High maternal antibody prevalence (>85%) was found for cytomegalovirus (CMV), herpes simplex virus (HSV), and rubella.
    • Antibodies to Toxoplasma gondii were present in 28% of subjects.
    • The lowest seroprevalence was observed for HBsAg (1.2%) and Treponema pallidum (0.9%).

    Conclusions:

    • Routine screening for rubella, syphilis, and hepatitis B is advocated for all pregnancies in Bahrain.
    • Routine serological testing for CMV and HSV is not recommended due to high prevalence.
    • Routine Toxoplasma antibody testing is not recommended due to lack of proven prevention and high costs.