Related Experiment Video
Updated: Jul 8, 2026

Use of Interferon-γ Enzyme-linked Immunospot Assay to Characterize Novel T-cell Epitopes of Human Papillomavirus
Published on: March 8, 2012
Patterns of genotype distribution in multiple human papillomavirus infections
L H S Oliveira1, M L G Rosa, S M B Cavalcanti
1Department of Microbiology and Parasitology, Fluminense Federal University, Niterói, RJ, Brazil. mipledy@centroin.com.br
Abstract:
The relationship between severe-grade cervical lesions and clusters of human papillomavirus (HPV) genotypes in a taxonomic classification was surveyed in 232 women with previous abnormal cytology. HPV co-infections were clustered according to phylogenetic criteria. Multiple infections were detected in 22.0% of the entire sample. Clade A10 (represented by HPV-6 and HPV-11) appeared more frequently in multiple infections than clade A9, which was represented by five of the most common high-risk types, including HPV-16. Although HPV-16 was the most frequent genotype, it was not more prevalent in multiple infections. Abortion and two or more sexual partners were risk-factors associated with HPV co-infections. Severe cervical dysplasia was associated with co-infections with oncogenic types from different clades, with the association being significant for the high-risk clades A7 and A9.
Related Concept Videos
Genital Herpes
Human Virome
Single Nucleotide Polymorphisms-SNPs
Herpes
