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Published on: September 5, 2011
Pregnancy outcomes after uterine artery occlusion: prospective multicentric study
Zdenek Holub1, Michal Mara, David Kuzel
1Department of Obstetrics and Gynecology, Baby Friendly Hospital, Kladno, Czech Republic. holubz@seznam.cz
Objective:
To assess the reproductive outcomes after laparoscopic uterine artery occlusion (LUAO) and uterine artery embolization (UAE) in women with symptomatic fibroids.
Design:
Prospective, clinical multicentric study.
Setting:
Endoscopic center in the department of obstetrics and gynecology at a hospital in the Czech Republic.
Patient(S):
Thirty-eight pregnant women after LUAO and 20 pregnant women after UAE.
Intervention(S):
Laparoscopic uterine artery occlusion and UAE.
Main Outcome Measure(S):
Pregnancy, abortion, preterm delivery, and live-birth rates.
Result(S):
Pregnancies after uterine embolization had a statistically significantly higher rate for spontaneous abortion (56%) than did pregnancies after surgical uterine artery occlusion (10.5%). The risk of malpresentation (20%) and the rate for cesarean section (80%) after UAE similarly were higher than was the risk after laparoscopic occlusion; however, these differences were not statistically significant. Also, there were no significant differences between the groups in preterm deliveries (15.3% in the LUAO group vs. 20% in the UAE group).
Conclusion(S):
Pregnancies of women who were treated with uterine embolization were at significantly increased risk for spontaneous abortion when compared with pregnancies of women treated with LUAO.
