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Closure of a Patent Foramen Ovale (PFO): An Intervention Sequence
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Closure of a Patent Foramen Ovale (PFO): An Intervention Sequence

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Prevalence of patent foramen ovale in patients with migraine

Asli Demirtaş Tatlidede1, Buket Oflazoğlu, Seden Erten Celik

  • 1Sişli Etfal Training and Research Hospital, Neurology Clinic, Istanbul, Turkey.

Agri : Agri (Algoloji) Dernegi'Nin Yayin Organidir = the Journal of the Turkish Society of Algology
|December 27, 2007
PubMed

Insights

Patent foramen ovale (PFO) is more common in migraine patients, particularly those with aura. This study found a higher prevalence of PFO in individuals experiencing migraines compared to healthy controls.

Area of Science:

  • Cardiology
  • Neurology

Background:

  • Migraine with aura is increasingly linked to patent foramen ovale (PFO).
  • Understanding the association between PFO and migraine is crucial for patient management.

Purpose of the Study:

  • To investigate the prevalence of PFO in patients with migraine.
  • To determine if PFO is more frequent in migraine patients, especially those with aura.

Main Methods:

  • A case-control study was conducted involving 53 migraine patients and 27 healthy controls.
  • Transthoracic echocardiography with contrast during Valsalva maneuver was used to detect intra-atrial right-to-left shunts (PFO).

Main Results:

  • Patent foramen ovale was significantly more frequent in the migraine group (p<.01).
  • PFO prevalence was 66.7% in migraine with aura, 47.4% in migraine without aura, and 22.2% in controls.

Conclusions:

  • Results support a significant association between PFO and migraine.
  • The link between PFO and migraine appears stronger in patients experiencing aura.

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