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Optical Sectioning and Visualization of the Intervertebral Disc from Embryonic Development to Degeneration
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Quantitative analysis of structural disorder in intervertebral disks using second harmonic generation imaging:

Karen M Reiser1, Clayton Bratton, Diego R Yankelevich

  • 1University of California, Davis, Department of Neurological Surgery, Davis, California 95616, USA. kmreiser@ucdavis.edu

Journal of Biomedical Optics
|January 1, 2008
PubMed
Summary

A new algorithm quantifies structural disorder in biological tissues using second harmonic generation (SHG) imaging. This method accurately measures tissue damage and can differentiate between reversible and irreversible injury.

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