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Myogenic growth factors can decrease extraocular muscle force generation: a potential biological approach to the

Brian C Anderson1, Stephen P Christiansen, Linda K McLoon

  • 1Department of Ophthalmology, University of Minnesota, 2001 6th Street SE, Minneapolis, MN 55455, USA.

Investigative Ophthalmology & Visual Science
|January 4, 2008
PubMed
Summary

Growth factors like BMP4, TGFbeta1, Shh, and Wnt3A can decrease extraocular muscle (EOM) force. These myogenic signaling factors offer a biological approach for strabismus treatment, potentially reducing muscle strength without toxins.

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