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Ex Vivo Infection of Human Lymphoid Tissue and Female Genital Mucosa with Human Immunodeficiency Virus 1 and Histoculture
Published on: October 12, 2018
The first community-based sexually transmitted disease/HIV intervention trial for female sex workers in China
Zunyou Wu1, Keming Rou, Manhong Jia
1National Centre for AIDS/STD Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, China.
Objectives:
This study was the first community-based intervention to test feasibility and effectiveness of an intervention targeting sex workers in China.
Design:
Prospective, community-based, pre/post-intervention trial.
Method:
Thirty establishments in Chengjiang, 34 in Ruili and 23 in Longchuan were selected for the study. The study participants were female sex workers. Out-reach workers visited the establishments to conduct intervention activities over 6 weeks. The activities included lectures, discussion, video and audio cassettes, and distribution of educational folders and condoms. Pre- and post-intervention cross-sectional surveys assessed changes in sexually transmitted disease (STD)/AIDS knowledge and condom use.
Results:
After the intervention, knowledge of the three HIV transmission routes increased from 25 to 88% (P < 0.01), knowledge that condoms can reduce the risk of STD/HIV infection increased from 56 to 94% (P < 0.01). Condom use at last sex and in the last three sexual encounters increased from 61 to 85% (P < 0.01) and from 41 to 70%, respectively. Multivariate analyses indicated that the intervention was an independent factor (P < 0.01) for these changes.
Conclusion:
The intervention programme was effective at increasing HIV/AIDS knowledge and condom use rates among sex workers in the community and should be expanded.
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