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Evaluation of screening tests for congenital cytomegalovirus infection

Naoki Inoue1, Shin Koyano

  • 1Department of Virology I, National Institute of Infectious Diseases, Tokyo, Japan. ninoue@nih.go.jp

The Pediatric Infectious Disease Journal
|January 5, 2008
PubMed

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Cytomegalovirus Disease

Cytomegalovirus (CMV) disease is caused by human cytomegalovirus, a double-stranded DNA virus of the Herpesviridae family. While primary CMV infection is often asymptomatic in immunocompetent individuals, the virus can cause severe disease in neonates and immunocompromised patients. CMV is the most common cause of congenital viral infection in the United States, and a major pathogen in solid organ and hematopoietic stem cell transplant recipients.CMV is transmitted via bodily fluids, sexual...