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Updated: Jul 8, 2026

Calcification of Vascular Smooth Muscle Cells and Imaging of Aortic Calcification and Inflammation
Published on: May 31, 2016
[Basic and clinical aspects of calcimimetics. Cinacalcet, effect and mechanisms of action]
Shohei Nakanishi1, Masafumi Fukagawa
1Toranomon Hospital, Nephrology Center, Japan.
Abstract:
Calcimimetics drug such as cinacalcet suppress the secretion of parathyroid hormone by sensitizing parathyroid calcium receptors to extracellular ionized calcium. Standard treatment for secondary hyperparathyroidism is associated with the risk of hypercalcemia, but cinacalcet don't induce elevation of serum calcium. And it is reported that cinacalcet attenuates parathyroid hyperplasia and it effects on other organs.
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