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Updated: Jul 8, 2026

Long-Term Mouse Spinal Cord Organotypic Slice Culture as a Platform for Validating Cell Transplantation in Spinal Cord Injury
Published on: April 12, 2024
[Spinal cord injury and regenerative medicine]
Sandino Estrada-Mondaca1, Alfonso Carreón-Rodríguez, María Del Carmen Parra-Cid
1Instituto Nacional de Rehabilitación, Grupo de Medicina Regenerativa, Unidad de Ingeniería de Tejidos, Mexico.
Abstract:
Spinal cord injury (SCI) is a trauma problem striking mainly working age adults, therefore affecting society beyond the victims family circle. Most of the victims of SCI will never recover; therapy for this type of injury consists basically on spinal cord support and stabilization. With the discovery of stem cells (SC), SCI treatment has been given another chance. Stem cells are responsible for tissue renewal throughout the individuals life, as well as tissue repair when needed. From the therapeutic point of view, the most appealing SC are those capable of generating a variety of tissues, those easily harvested, and finally, those ethically unquestioned. This article summarizes some studies carried with SC of various origins and their application to SCI treatment.
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