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Updated: Jul 8, 2026

Measuring Psoriasis Severity at Home
Published on: March 1, 2024
Axial disease in psoriatic arthritis
1Centre for Prognosis Studies in Rheumatic Diseases, Toronto Western Hospital, 399 Bathurst Street, 1E-410B, Toronto, Ontario, M5T 2S8, Canada. dafna.gladman@utoronto.ca
Psoriatic spondylitis, a form of axial disease in psoriatic arthritis, has varied definitions and prevalence. This review covers its features, development, outlook, and management.
Area of Science:
- Rheumatology
- Immunology
- Radiology
Background:
- Axial disease in psoriatic arthritis lacks a consistent definition, leading to varied prevalence estimates (25%-70%).
- Definitions range from isolated sacroiliitis to ankylosing spondylitis-like criteria.
- Understanding axial involvement is crucial for psoriatic arthritis management.
Purpose of the Study:
- To review the prevalence, clinical, and radiologic features of psoriatic spondylitis.
- To explore the pathogenesis, prognosis, and treatment of psoriatic spondylitis.
- To consolidate current knowledge on axial disease in psoriatic arthritis.
Main Methods:
- Literature review of studies on psoriatic arthritis and axial involvement.
- Synthesis of data on prevalence, clinical presentation, and imaging findings.
- Analysis of pathogenesis, prognostic factors, and therapeutic options.
Main Results:
- Prevalence of axial disease in psoriatic arthritis is highly variable based on definition.
- Clinical and radiologic features overlap with other spondyloarthropathies.
- Psoriatic spondylitis impacts prognosis and treatment strategies.
Conclusions:
- A standardized definition for axial disease in psoriatic arthritis is needed.
- Psoriatic spondylitis represents a significant subset of psoriatic arthritis with distinct characteristics.
- Further research is warranted to optimize diagnosis and treatment.
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