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Serological immunoreactivity against colon cancer proteome varies upon disease progression

Lucia De Monte1, Francesca Sanvito, Stefano Olivieri

  • 1Proteome Biochemistry, Tumor Immunology, Mass Spectrometry, Pathology, Surgery, Experimental Immunology, Cancer Immunotherapy and Gene Therapy Program, San Raffaele Scientific Institute, via Olgettina 58, 20132 Milan, Italy.

Journal of Proteome Research
|January 9, 2008
PubMed

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Tumor progression is a phenomenon where the pre-formed tumor acquires successive mutations to become clinically more aggressive and malignant. In the 1950s, Foulds first described the stepwise progression of cancer cells through successive stages.
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