[Variant Brugada syndrome--mild ST segment elevation in inferior leads and aborted sudden cardiac death]
Piotr Kukla1, Marek Jastrzebski, Bogumiła Bacior
1Oddział Wewnetrzny, Szpital Specjalistyczny im. H. Klimontowicza, Gorlice.
Insights
A man survived sudden cardiac death (SCD) due to variant Brugada syndrome. Persistent ST segment elevations in inferior leads may indicate this condition, even with negative cardiac markers.
Area of Science:
- Cardiology
- Electrophysiology
- Genetics
Background:
- Sudden cardiac death (SCD) is a critical condition requiring accurate diagnosis.
- Variant Brugada syndrome is an inherited arrhythmia syndrome.
- ST segment elevation in ECG can mimic acute coronary syndrome.
Observation:
- A 48-year-old man survived aborted SCD with inferior ST segment elevation.
- Initial investigations for acute coronary syndrome were negative.
- Electrophysiological study and ajmaline test were positive for Brugada syndrome.
Findings:
- The patient was diagnosed with variant Brugada syndrome.
- Persistent inferior ST segment elevation was a key diagnostic feature.
- A prolonged PQ interval and family history of SCD were noted.
Implications:
- Persistent ST segment elevation in inferior leads may be a marker for variant Brugada syndrome.
- This case highlights the importance of considering Brugada syndrome in unexplained SCD.
- Early diagnosis and management are crucial for preventing future cardiac events.
Abstract:
We describe a case of an otherwise healthy 48-year-old man who survived aborted sudden cardiac death (SCD). His ECG showed ST segment elevation in inferior leads, therefore an acute coronary syndrome was suspected. However, serial troponin T and CPK-MB were negative, echocardiogram was unremarkable and exercise test was negative. On the basis of electrophysiological study, positive ajmaline test, persistent ST segment elevation in inferior leads and other clinical features (PQ interval of 240 ms, family history of SCD) a diagnosis of variant Brugada syndrome was made. Persistent ST segment elevations in inferior leads can be a marker of variant Brugada syndrome.
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