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Updated: Oct 27, 2026

In Vitro Permeation of FITC-loaded Ferritins Across a Rat Blood-brain Barrier: a Model to Study the Delivery of Nanoformulated Molecules
Published on: August 22, 2016
[Effect of emulsions of carbon perfluoride compounds on the blood plasma complement system and functional state of
Abstract:
Experiments were conducted in vitro on rabbits to study the effect of emulsions based on composition of carbon perfluorides (decalin perfluoride/methyl cyclohexyl piperidine perfluoride) and proxanol (P-268) on the blood complement system. It is shown that despite preservation of the composition some emulsions activate complement others fail to do this. Intravenous infusion of complement-activating emulsion in a test-dose leads to early neutropenic reaction in the peripheral blood of rabbits and intensified power of low frequency rhythms in the electrocorticogram.

