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A novel leishmanicidal labdane from Polyalthia macropoda
P Richomme1, M C Godet, F Foussard
1C.E.P.M., Faculté de Pharmacie, Angers, France.
Planta Medica
|December 1, 1991
Abstract:
A new diterpene, (4S,9R,10R) methyl 18-carboxy-labda-8,13(E)-diene-15-oate has been obtained from the stem barks of Polyalthia macropoda (Annonaceae). This labdanic derivative was identified on the basis of spectroscopic data and is biologically active against the promastigote Leishmania donovani donovani.