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Alcohol consumption and renal cell cancer risk in two Italian case-control studies
C Pelucchi1, C Galeone, M Montella
1Istituto di Ricerche Farmacologiche Mario Negri, Milan, Italy. pelucchi@marionegri.it
Background:
There is some evidence that alcohol consumption is inversely associated with renal cell cancer (RCC), but the issue is still unclear.
Patients And Methods:
We investigated the relation using data from two Italian multicentric case-control studies conducted from 1985 to 2004, including a total of 1115 incident, histologically confirmed cases and 2582 controls hospitalised with acute, non-neoplastic conditions.
Results:
Compared with non-drinkers, the multivariate odds ratios (ORs) of RCC were 0.87 [95% confidence interval (CI) 0.73-1.04] for
Conclusions:
This pooled analysis found an inverse association between alcohol drinking and RCC. Risks continued to decrease even above eight drinks per day (i.e. >100 g/day) of alcohol intake, with no apparent levelling in risk.
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