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Updated: Jul 8, 2026

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Intermolecular Cope-type hydroamination of alkynes using hydrazines

Pamela H Cebrowski1, Jean-Grégoire Roveda, Joseph Moran

  • 1Centre for Catalysis Research and Innovation, Department of Chemistry, University of Ottawa, Ottawa, ON, Canada.

Chemical Communications (Cambridge, England)
|January 12, 2008
PubMed
Summary

This study demonstrates metal-free intermolecular hydroamination of aryl acetylenes using methylhydrazine. The reaction preferentially forms linear, anti-Markovnikov hydrazones upon heating.

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