Stillbirths in Macaca fascicularis.
Wacharaporn Sesbuppha1, Surachai Chantip, Edward J Dick
1National Laboratory Animal Center, Mahidol University, Nakornprathom, Thailand.
Journal of Medical Primatology
|January 16, 2008
Summary
Stillbirths in Macaca fascicularis monkeys are common, with most cases having no clear cause. Fetal trauma was identified as the most frequent identifiable reason for stillbirth in this primate colony.
Area of Science:
- Veterinary Medicine
- Primatology
- Reproductive Biology
Background:
- Stillbirths in non-human primates signify a failure of the maternal-fetal-placental unit.
- Causes can be endogenous, undetermined, or environmental.
Purpose of the Study:
- To retrospectively analyze stillbirth incidence and causes in a Macaca fascicularis colony.
- To identify common etiological factors contributing to stillbirths in this primate model.
Main Methods:
- Retrospective review of 236 stillborn cases and their dams over a 7-year period.
- Analysis of fetal, maternal, and placental factors associated with stillbirths.
Main Results:
- The 7-year stillbirth incidence was 11.99%.
- Most stillbirths (61.02%) were of undetermined etiology.
- Fetal trauma (22.46%) was the most common identifiable cause, followed by dystocia (9.75%).
Conclusions:
- The majority of stillbirths in this Macaca fascicularis colony were of undetermined origin.
- Fetal trauma represents the primary identifiable cause of stillbirth in this population.
