Related Experiment Video
Updated: Feb 10, 2026

Author Spotlight: Advancing VRL Diagnosis Using Cell-Free DNA Extraction from Vitreous Humor
Published on: January 12, 2024
Displacement of retained subfoveal perfluorocarbon liquid after vitreoretinal surgery
Valérie Le Tien1, Vincent Pierre-Kahn, Frédéric Azan
1Department of Ophthalmology, Hôpital Foch, 40 Rue Worth, 92150, Suresnes, France.
Objective:
To report a novel surgical procedure to displace retained subfoveal perfluorocarbon liquid (PFCL).
Methods:
Retrospective cases series. Three patients had retained subfoveal droplets after PFCL was used in vitrectomy repair of retinal detachment. In each case, submacular PFCL was displaced to the subretinal space in the inferior periphery. A retinal detachment at the posterior pole and the inferior periphery was created by injecting balanced salt solution through a retinal puncture near the inferotemporal vessels. Fluid-air exchange was performed, followed by short-term postoperative upright head positioning.
Results:
In all cases, PFCL droplets were successfully displaced toward the inferior periphery, with good visual recovery.
Conclusion:
This procedure seems to be safe and is an alternative to direct aspiration of PFCL through a juxtafoveal retinotomy, which risks damage to the foveal region.
Related Concept Videos
Displacement Current
Position and Displacement
Position and Displacement Vectors
Further, several important kinds of...
Significance of Displacement Current
Angular Velocity and Displacement
EDTA: Direct, Back-, and Displacement Titration
Direct titration involves buffering the metal ion solution to the desired pH and directly titrating with standard EDTA until the endpoint. The optimum pH ensures a large conditional formation constant of metal−EDTA and visibility of the free indicator color in the solution. In addition, auxiliary complexing reagents are used to prevent the precipitation of metal hydroxides...

