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Updated: Jul 8, 2026

Percutaneous Hepatic Perfusion (PHP) with Melphalan as a Treatment for Unresectable Metastases Confined to the Liver
Published on: July 31, 2016
[Anaesthesia for patients with phaeochromocytoma - specifics, potential complications and drug strategies]
1Klinik für Anästhesio logie und operative Intensivmedizin des Krankenhauses Köln-Merheim. knuettgend@klinikenkoeln.de
Abstract:
Perioperative management of patients with phaeochromocytoma requires detailed knowledge on the pathophysiology and potential complications. Intraoperatively, hypertensive crisis and tachyarrhythmias may occur resulting from massive catecholamine release. Thus, preoperative treatment with the alpha-antagonist phenoxybenzamine is obligatory. In contrast, sodium nitroprusside is the substance of choice for intraoperative control of blood pressure. alpha-blocking agents may be used in phaeochromocytoma but only under sufficient alpha-blockade. Removal of a malignant tumour of the adrenal gland may induce massive haemorrhage, and thus anaesthetic management has to be modified.
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