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Updated: Jul 8, 2026

A 3D Organotypic Melanoma Spheroid Skin Model
Published on: May 18, 2018
[Clinico-morpho-sonographic parallels in skin melanoma]
Abstract:
Data on sonographic features of different variants of skin melanoma are presented. Relationship between skin to tumor thickness ratio and invasion depth (Clark) or tumor thickness (Breslow) were found. Tumor extent was effectively identified by ultrasound tomography of primary focus preoperatively. Such patterns of melanoma blood supply as "avascular" (superficial tumor) and "vascular" (node-like tumor) were established. A "tree-like" vascular pattern was typical of melanoma in color Doppler imaging. Tumor with such pattern had poor prognosis.
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