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Adenosine deaminase, Ada, is in mouse chromosome 2H3, and is not allelic with wasted, wst
C M Abbott1, E P Evans, M Burtenshaw
1MRC Radiobiology Unit, Chilton, Didcot, U.K.
Biochemical Genetics
|December 1, 1991
Abstract:
The adenosine deaminase locus (Ada) in the mouse has been localized by in situ hybridization to band 2H3. Linkage analysis of backcross data has shown that Ada is 13.8 +/- 2.7 cM from the coat texture mutant, ragged, Ra. From the results of earlier work (Abbott, C. M., et al., Proc. Natl. Acad. Sci. USA 83:693, 1986), it had been suggested that wst was a low-activity allele of Ada, but this cannot be so because Ada and wst have been found to be nonallelic.