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Acute eosinophilic pneumonia with intramuscular progesterone after in vitro fertilization
Amir M Khan1, Sunit Jariwala, Harry Jay Lieman
1Department of Pulmonary Medicine, Pulmonary and Critical Care Center, Bronx, New York 10463, USA. dramirkhan@hotmail.com
Objective:
To report an unusual case of acute eosinophilic pneumonia that was associated with IM P in oil after IVF.
Design:
Case report.
Setting:
Academic teaching hospital.
Patient(S):
A 35-year-old primigravid female who developed acute eosinophilic pneumonia after administration of IM P in oil as luteal-phase support after IVF.
Intervention(S):
Corticosteroid therapy; replacement of IM P with intravaginal preparation.
Main Outcome Measure(S):
Evaluation of blood eosinophil counts along with clinical symptoms and chest radiograph findings at initial presentation and throughout the hospital course.
Result(S):
After the noted interventions, there was a marked improvement of clinical symptoms, chest radiograph findings, and eosinophilia.
Conclusion(S):
Although allergic reactions to IM P-in-oil administration are exceedingly rare, clinicians caring for patients using these products should be aware of potential adverse reactions and subsequent management.
