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Classifying tetrahydrobiopterin responsiveness in the hyperphenylalaninaemias

U Langenbeck1

  • 1Institute of Human Genetics, University Hospital, Theodor-Stern-Kai 7, D-60590, Frankfurt/Main, Germany. u.langenbeck@em.uni-frankfurt.de

Journal of Inherited Metabolic Disease
|January 23, 2008
PubMed
Summary

Calculating the half-life (t½) of phenylalanine (Phe) in blood offers a superior method for assessing tetrahydrobiopterin (BH(4)) responsiveness in hyperphenylalaninaemia patients compared to percentage reduction. This approach provides a more comprehensive and reliable assessment for treatment decisions.

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