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Related Experiment Video

Updated: Jul 8, 2026

Fluorescence Molecular Tomography for In Vivo Imaging of Glioblastoma Xenografts
07:52

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Published on: April 26, 2018

Metastatic brain tumor surgery using fluorescein sodium: technical note.

T Okuda1, K Kataoka, M Taneda

  • 1Department of Neurosurgery, Kinki University School of Medicine, Osaka, Japan. okuda@neuro-s.med.kindai.ac.jp

Minimally Invasive Neurosurgery : MIN
|January 23, 2008
PubMed
Summary

High-dose fluorescein sodium enables effective fluorescence-guided resection for metastatic brain tumors. This safe, inexpensive, and easy-to-use technique improves radical tumor removal in neurosurgery.

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Area of Science:

  • Neurosurgery
  • Oncology
  • Medical Imaging

Background:

  • Glioma surgery increasingly uses fluorescence-guided resection (5-ALA, fluorescein sodium) for radical tumor removal.
  • No specific technique exists for metastatic brain tumor surgery.

Observation:

  • High-dose fluorescein sodium was employed for fluorescence-guided resection in 13 metastatic brain tumor cases.
  • Effective tumor stainability was achieved in all cases.

Findings:

  • Fluorescein sodium demonstrated effective stainability in all 13 metastatic brain tumor surgeries.
  • The technique is inexpensive, safe, and easy to use, requiring no special equipment.

Implications:

  • Fluorescein sodium is a beneficial tool for improving radical resection rates in metastatic brain tumor surgery.
  • This method offers a practical and accessible approach to enhance neurosurgical outcomes for brain metastases.