Related Experiment Video
Updated: Jul 8, 2026

Bronchial Thermoplasty: A Novel Therapeutic Approach to Severe Asthma
Published on: November 4, 2010
[The use of anti-asthmatic medication among Danish elite athletes]
Thomas K Lund1, Lars Pedersen, Vibeke Backer
1Bispebjerg Hospital, Lungemedicinsk Forskningsenhed, Lungemedicinsk Klinik L, København NV. tclund@dadlnet.dk
Introduction:
The prevalence of asthma and the use of anti-asthmatic medication is high among elite athletes. Elite athletes require a TUE certificate (Therapeutic Use Exemption) if they require anti-asthmatic medication which is on the prohibited list. The aim of the study was to determine the distribution of Danish TUE certificates and to examine the use of anti-asthmatic medication among Danish elite athletes.
Materials And Methods:
A cross-sectional study of all applications for TUE certificates in 2005 was carried out. We focused on applications including anti-asthmatic medication. All applications resulted in certificates being issued.
Results:
A total of 694 TUE certificates were issued. Of these, 445 (64%) concerned anti-asthmatic medication. Short-acting beta-2-agonists (SABA) were the most frequent medication (79%). Only 2% received long-acting beta-2-agonists (LABA) as single therapy. Inhaled steroids were used by 69%. Swimmers received significantly higher doses of inhaled steroids compared to all others athletes (1031 microg/day (148); p=0.01). The applications for TUE certificates were generally handled by general practitioners (78%).
Conclusion:
Most TUE certificates issued in 2005 concerned anti-asthmatic medication. Only a few athletes were treated with non-recommended anti-asthmatic medication like LABA as single therapy. Swimmers received higher doses of inhaled steroids compared to all others athletes. Most of the applications for TUE certificates were handled by general practitioners.
Related Concept Videos
Antiasthma Drugs: Mast Cell Stabilizers and Anti-IgE Drugs
Mast cell stabilizers, such as cromolyn (also known as sodium cromoglycate) and nedocromil (Tilade), are effective drugs in asthma management. These stabilizers hinder histamine release by skillfully obstructing the activation of mast cells and other cellular entities. Notably, they navigate this task without...
Antiasthma Drugs: β2-Adrenoceptor Agonists
One class of bronchodilators includes β2-adrenoceptor agonists. These agents target the β2-adrenoceptors located on bronchial smooth muscle cells. By stimulating these receptors, β2-agonists induce relaxation in these...
Asthma-IV: Diagnostic and Management
Clinical Assessment for Asthma:
This is the first step in diagnosing and managing asthma. It includes:
Asthma I: Introduction
Antiasthma Drugs: Methylxanthines
Theophylline is thought to inhibit phosphodiesterase enzymes, increasing intracellular levels of cyclic adenosine monophosphate (cAMP) and cyclic guanosine monophosphate (cGMP). This rise in cAMP and cGMP concentrations stimulates cardiac function,...
Antiasthma Drugs: Leukotriene Modifiers
Leukotriene modifiers work through two distinct mechanisms:

