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Updated: Jul 8, 2026
07:54
Detection of Rabies IgG and IgM Antibodies Using the Rabies Indirect Fluorescent Antibody Test
Published on: January 19, 2024
An infant with fever and stridor
Derek S Wheeler1, Derrick J Dauplaise, John S Giuliano
1Division of Critical Care Medicine, Cincinnati Children's Hospital Medical Center and Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, OH 45229-3039, USA. derek.wheeler@cchmc.org
Pediatric Emergency Care
|January 24, 2008
Summary
Infectious upper airway obstruction, including epiglottitis (supraglottitis), remains a pediatric risk despite vaccines. Prompt recognition and treatment are crucial for preventing severe outcomes in children.
Area of Science:
- Pediatric Infectious Diseases
- Otolaryngology
- Emergency Medicine
Background:
- The incidence of infectious upper airway obstruction has shifted due to widespread vaccination, notably against diphtheria and Haemophilus influenzae type B.
- Despite these advances, infectious etiologies of upper airway obstruction continue to pose significant morbidity and mortality risks in children.
Observation:
- Epiglottitis, also termed supraglottitis, is a severe bacterial infection affecting the epiglottis and adjacent laryngeal structures.
- While vaccination has reduced invasive Haemophilus influenzae type B cases, supraglottitis remains a critical concern for pediatric healthcare providers.
Findings:
- Physicians must maintain awareness of the diverse clinical presentations of pediatric upper airway obstruction.
- Early and accurate diagnosis, alongside prompt, appropriate management, is essential for positive patient outcomes and preventing life-threatening complications.
Implications:
- Understanding the evolving landscape of infectious upper airway obstruction is vital for pediatricians and emergency physicians.
- Even without classic symptoms, prompt recognition and management of supraglottitis can avert severe consequences in pediatric patients.
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